PE Mouse anti-Rabbit IgG (Fc) Monoclonal Antibody for Flow Cytometry - P01870

Core Product Specifications and Parameters

Biological Background: Ig gamma chain C Region Function and Localization

• The target protein is the constant region of the rabbit immunoglobulin gamma heavy chain (IgG Fc), which mediates antibody effector functions.
• It is composed of immunoglobulin-like domains, characteristic of antibody constant regions and responsible for interactions with Fc receptors and complement proteins.
• The protein features internal repeats, a hallmark of the immunoglobulin superfamily, contributing to its stable structure.
• Its primary sequence has been confirmed by direct protein sequencing, and its three-dimensional structure has been resolved (UniProt keyword: 3D-structure).
• As part of the reference proteome for Oryctolagus cuniculus, it is a well-characterized component of the rabbit immune system.

Experimental Guidance and Technical Tips

• The antibody is directly conjugated to PE, a bright fluorophore, making it ready-to-use for flow cytometry without secondary detection steps.
• The immunogen corresponds to the Fc region of rabbit IgG, ensuring specific binding to rabbit IgG regardless of antigen specificity; validate in the relevant sample system.
• For flow cytometry, titrate the antibody to determine the optimal concentration for your cell type and experimental conditions, and include appropriate isotype controls.
• Cross-reactivity with other species is not expected based on the immunogen design, but should be confirmed if used on non-rabbit samples.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers comprehensive one-stop access to IVD raw materials, supporting your needs from concept to clinic. This PE-conjugated anti-rabbit IgG (Fc) monoclonal antibody is part of our portfolio for immunological detection workflows, and we can supply validated antibody pairs, bulk ancillary reagents, and custom sourcing for rare targets. Partner with us to streamline your diagnostic development with reliable raw materials and expert guidance.